Nemesis includes twelve basic delay effect engines, with more effects available in the Neuro Mobile app. Existing effect engines can also be further edited using the Neuro App's expanded set of adjustable parameters.

• Slapback: synonymous with rockabilly guitar effects, Slapback offers a short single-repetition echo based on early tape delay machines.
• Digital: a classic clear digital delay with optional delay time modulation. The intensity knob controls the filtering, allowing high-pass filters (creating a thinner delay sound) or low-pass filters (creating a warmer delay sound). The 12 o'clock position on the intensity knob offers a 100% pure, unfiltered delay. Nemesis features a 56-bit signal path with a 24-bit delay line for impeccably clean repetitions.
• Diffuse: a delay line with a diffusion effect that blurs the attack of the repeated signal, softening it and allowing it to blend more easily with the unprocessed dry signal. This creates an ethereal sound reminiscent of classic "oil-in-can" delay systems.
• Analog: the sound of classic bucket brigade analog delays. Successive delays are warm, resonant, and increasingly lo-fi.
• Tape: a detailed recreation of classic multi-head tape delays. Tape captures all the flutter, warmth, and character that give vintage tape delay machines like Echoplex and Space Echo their classic charm.
• Noise Tape: a detailed recreation of classic fixed-head tape delays. Noise Tape is grainier and darker than the Tape engine, capturing the sound of old or damaged tape.
• Degrade: a primitive lo-fi digital delay with bit crushing and sample rate reduction. This creates unique retro sounds with varying amounts of distortion, noise, and aliasing.
• Shifter: a delay with polyphonic pitch shifting on the delayed signal. Choose between octaves (up or down), thirds, fourths, and minor or major fifths.
• Helix: this angelic delay effect combines reverse delay with an octave shifter to create a strange, bright delay that fades out in the upper frequency range.
• Reverse: the classic reverse tape sound that became popular through several iconic psychedelic guitarists who will remain anonymous. Nemesis creates several overlapping reverse delays that regularly fade and disappear to create a pulsing tremolo effect.
• Sweeper: a resonant low-pass filter slowly sweeps through the frequency range, creating a synth-like undulating effect.
• Rhythmic: Nemesis's delay line contains 6 taps. This allows for the creation of rhythmic patterns in the delay effect. The Rhythmic effect uses 4 taps to create a wide variety of rhythms.